Vocalo.org
I discovered this station on my way home from Chicago yesterday. It is listener-supplied (much of it original) content mixed with the familiar. There are interviews mixed in with music, mixed in with poetry. At first, it took a bit to get into the format, but now I love it - especially because if I hear something awesome, I can come home and search their site for the file and hear it again, or download it.
It’s radio 2.0.